Page and her team measured the response to diet soda in three ways.
"It is precisely people with obesity who disproportionately suffer from a strong drive to eat high-calorie foods," says Laura Schmidt, a professor of health policy at the University of California, San Francisco.
But this finding suggests that diet drinks sweetened with sucralose could be disadvantageous to the people who could benefit most from an effective diet strategy. The study notes that most earlier research focused on males and people of normal weight. "They were very important factors in the way that the brain responded to the artificial sweetener." "I think what was most surprising was the impact of body weight and biological sex," Page says. In contrast, the study found males and people of healthy weight did not have an increase in either brain reward activity or hunger response, suggesting they're not affected in the same way. "We found that females and people with obesity had greater brain reward activity" after consuming the artificial sweetener, says study author Katie Page, a physician specializing in obesity at the University of Southern California.īoth groups also had a reduction in the hormone that inhibits appetite, and they ate more food after they consumed drinks with sucralose, compared with after regular sugar-sweetened drinks. Yet, new research shows they also can leave people with increased food cravings.Ī study published recently in JAMA Network Open adds to the evidence that drinks made with sucralose may stimulate the appetite, at least among some people, and the study gives some clues as to why. True, they deliver the fizz and taste of a soda experience, without the calories. The "diet" in diet drinks may be a false promise for some soda lovers.
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